From: Is there a role for oral misoprostol in labor induction for prelabor rupture of membranes at term?
 | Oral Misoprostol (n = 493) | IV Oxytocin (n = 296) | Odds Ratio 95% CI | p-value |
---|---|---|---|---|
Time from PROM to delivery (mean ± s.d., mean, hour: min) | 1190 ± 26.7 19:48 | 856.9 ± 33.6 14:15 | N/A | < 0.001 |
Time from induction to delivery (minutes, mean ± s.d.± hour: min) | 671.6 ± 26.1 11:10 | 453 ± 27.5 7:33 | N/A | < 0.001 |
Time in labor ward (minutes, mean, s.d. hour: min) | 233.7 ± 10.5 3:55 | 471 ± 13.8 7:51 | N/A | < 0.001 |
Spontaneous vaginal delivery (n,%) | 418 (84.8%) | 251 (84.8%) | 1.0 0.7–1.5 | 0.5 |
Operative vaginal delivery (n,%) | 53 (10.8%) | 37 (12.5%) | 0.84 0.5–1.3 | 0.2 |
Cesarean delivery (n,%) | 22 (4.5%) | 9 (3.0%) | 1.5 0.7–3.3 | 0.2 |
Vaginal birth within 24 h of PROM (n,%) | 376 (76.3%) | 259 (87.5%) | 0.6 0.4–0.9 | < 0.001 |
Vaginal birth within 48 h of PROM (n,%) | 462 (93.7%) | 282 (95.2%) | 0.7 0.4–1.4 | 0.2 |
Vaginal delivery within 24Â h of labor induction | 429 (87%) | 270 (92%) | 0.6 0.4-1.0 | 0.04 |
Vaginal delivery within 48 h of labor induction | 466 (94.5%) | 285 (96.2%) | 0.7 0.3–1.4 | 0.13 |
Postpartum hemorrhage (n,%) | 10 (2.02%) | 12 (4.0%) | 0.4 0.2–0.9 | 0.02 |
Placental abruption (n,%) | 0 | 0 | N/A | N/A |
Chorioamnionitis (n,%) | 9 (1.82%) | 4 (1.4%) | 1.4 0.4–4.4 | 0.3 |
Shoulder Dystocia (n,%) | 3 (0.6%) | 0 | N/A | N/A |
Postpartum Readmission (n,%) | (0.4%) 2 | 2 (0.7%) | 0.6 0.1–4.2 | 0.3 |
Combined Adverse Maternal Outcome (n,%) | 24 (4.9%) | 18 (6.0%) | 0.8 0.4–1.4 | 0.2 |