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Table 3 Odds ratio of maternal CDKAL1 genetic marker on APO and its components

From: Associations of maternal cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1(CDKAL1) gene variants with adverse pregnancy outcome in Chinese women

Outcomes

Adjusted model 1

Adjusted model 2

OR (95% CI)

P

OR (95% CI)

P

APO

2.51 (1.47,4.28)

< 0.001

2.52 (1.48,4.30)

< 0.001

Birth weight of neonates

    

Normal birth weight

-

-

-

-

Low birth weight

19.80 (2.15,182)

0.008

20.62 (2.07,205)

0.010

Macrosomia

2.40 (1.17,4.93)

0.017

2.39 (1.16,4.91)

0.018

Preterm birth

2.28 (0.84,6.19)

0.105

2.36 (0.86,6.43)

0.094

  1. Abbreviations: APO, adverse pregnancy outcome; CDKAL1, cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1; OR, odds ratio; CI, confidence interval
  2. Adjusted model 1, adjusted for age, pre-pregnancy body mass index, family history of diabetes in first degree relatives, parity, education, Han ethnicity, hypertension, infant gender, and body height of neonates
  3. Adjusted model 2, further adjusted for gestational diabetes mellitus, in addition to the variables in the adjusted model 1
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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