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Table 2 The relationship between the type of vaccination, the number of vaccine doses, as well as the time of vaccination and miscarriage in pregnant women referring to comprehensive health service centers (n-610)

From: Comparing the maternal and neonatal outcomes in vaccinated and unvaccinated pregnant women against COVID-19: a retrospective cohort study

Miscarriage

Variable

 

Not occurred

occurred

Odds ratio* (confidence interval 95%)

P value

vaccination type

Unvaccinated (n-330)

Sinopharm (n-225)

Other vaccines (n-21)

Pre-pregnancy vaccine (n-34)

291 (88.8)

213 (94.7)

20 (95.2)

27 (79.4)

39 (11.8)

12 (5.3)

4 (4.8)

7 (20.6)

1.000

0.376 (0.188–0.750)

0.320 (0.041–2.491)

2.266 (0.899–5.712)

0.003

number of vaccine doses during pregnancy

Unvaccinated (n-364)

One dose (n-91)

Two dose (n-139)

Three dose (n-16)

318 (87.4)

79 (86.8)

138 (99.3)

16 (100)

46 (12.6)

12 (13.2)

1 (0.7)

0

1.000

1.022 (0.505–2.070)

0.041 (0.005–0.301)

-

0.019

timing of vaccination during pregnancy

Unvaccinated (n-364)

At least one dose in the first trimester (n-102)

At least one dose in the second trimester (n-120)

At least one dose in the third trimester (n-24)

318 (87.4)

90 (88.2)

119 (99.2)

24 (100)

46 (12.6)

12 (11.8)

1 (0.8)

0

1.000

0.818 (0.407–1.643)

0.048 (0.006–0.359)

-

0.031

  1. * Multiple logistic regression analysis. In calculating the odds ratio and 95% confidence interval, the effect of the confounding variables “history of pregnancy outcomes”, “underlying disease”, and “number of miscarriage history” has been adjusted. ** Including: Elective abortion, spontaneous abortion, and these categories were aggregated with each other in order to use logistic regression