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Fig. 4 | BMC Pregnancy and Childbirth

Fig. 4

From: LC-MS/MS assay to confirm that the endogenous metabolite L-Arginine promotes trophoblast invasion in the placenta accreta spectrum through upregulation of the GPRC6A/PI3K/AKT pathway

Fig. 4

L-Arginine promotes HTR-8/Svneo invasion. A. Cytotoxicity of L-Arginine. B. Pro-proliferative effect of L-Arginine. C. Promotion of cell migration by L-Arginine. D. Promotion of cell invasion by L-Arginine. E. RT-qPCR detection of GPRC6A, PI3K, AKT, MMP2, and MMP9 expression. F. Western blot detection of p-PI3K, PI3K, p-AKT, AKT, GPRC6A, MMP2, and MMP9 expression. *p < 0.05 vs. Control

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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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