Table 2 Comparison of COS conditions and pregnancy outcomes between PCOS and control group
Variables | PCOS (n = 167) | Control (n = 266) | P-value |
|---|---|---|---|
Antral follicle count (AFC) | 24.00 (20.00, 29.00) | 14.00 (10.00, 18.00) | < 0.001 |
Infertility diagnosis | Â | Â | Â |
Primary infertility (%) | 62.87 (105/167) | 59.40 (158/266) | 0.471 |
Secondary infertility, (%) | 37.13 (62/167) | 40.60 (108/266) | 0.471 |
ICSI cycles (%) | 15.57 (26/167) | 25.94 (69/266) | 0.011 |
Duration of stimulation (days) | 10.42 ± 2.12 | 10.91 ± 2.00 | 0.016 |
Gn priming dosage (IU) | 150.00 (125.00, 175.00) | 187.50 (150.00, 225.00) | < 0.001 |
Total dose of Gn (IU) | 1650.00 (1350.00, 2100.00) | 2250 (1650.00, 2775.00) | < 0.001 |
E2 on hCG day (pg/ml) | 2546.29 (1809.50, 3460.50) | 1957.00 (1353.82, 2701.72) | < 0.001 |
Retrieved oocytes | 11.00 (9.00, 15.00) | 11.00 (8.00, 14.00) | 0.097 |
No. of MII oocytes | 9.00 (7.00, 13.00) | 8.00 (6.00, 11.00) | 0.026 |
Fertilized oocytes (2PN) | 6.00 (4.00, 8.00) | 6.00 (4.00, 8.00) | 0.312 |
No. of available embryos of Day 3 | 6.00 (4.00, 9.00) | 5.00 (4.00, 7.00) | 0.005 |
No. of blastocysts formed | 2.00 (0.00, 5.00) | 2.00 (0.00, 4.00) | 0.247 |
Rate of blastocyst formed (%) | 75.00 (50.00, 87.00) | 70.00 (50.00, 100.0) | 0.388 |
No. of high quality blastocysts | 0.00 (0.00, 1.00) | 0.00 (0.00, 0.00) | 0.003 |
Rate of high quality blastocysts (%) | 25.00 (0.00, 50.00) | 0.00 (0.00,33.00) | 0.023 |
No. of embryos transferred | 2.00 (2.00, 2.00) | 2.00 (2.00, 2.00) | 0.840 |
Endometrial thickness (mm) | 10.58 ± 2.35 | 11.70 ± 2.69 | < 0.001 |
Pregnancy rate, (%) | 62.87 (105/167) | 62.41(166/266) | 0.922 |
Clinical pregnancy rate (%) | 47.90 (80/167) | 52.26 (139/266) | 0.378 |
Miscarriage rate (%) | 23.75 (19/80) | 10.79 (15/139) | 0.011 |
Live birth rate (%) | 36.53 (61/167) | 46.62 (124/266) | 0.039 |