Table 4 Comparison of COS conditions and pregnancy outcomes in high-BMI individuals
Variables | PCOS (n = 77) | Control (n = 100) | P-value |
|---|---|---|---|
Antral follicle count (AFC) | 24.00 (20.00, 29.50) | 14.50 (10.00, 19.00) | < 0.001 |
Infertility diagnosis | Â | Â | Â |
Primary infertility (%) | 61.04 (47/77) | 55.00 (55/100) | 0.420 |
Secondary infertility (%) | 38.96 (30/77) | 45.00 (45/100) | 0.420 |
ICSI cycles (%) | 16.88 (13/77) | 24.00(24/100) | 0.248 |
Duration of stimulation (days) | 10.57 ± 2.41 | 11.28 ± 2.38 | 0.052 |
Gn priming dosage (IU) | 150 (150, 200.00) | .. 200.00 (150.00, 225.00) | 0.001 |
Total dose of Gn (IU) | 1800 (1500, 2400) | 2256.25 (1800.00, 3168.90) | 0.001 |
E2 on hCG day (pg/ml) | 2566.50 (1818.50, 3164.25) | 1813.93 (1173.50, 2408.75) | < 0.001 |
Retrieved oocytes | 11.00 (9.00, 15.00) | 10.00 (7.00, 13.75) | 0.043 |
No. of MII oocytes | 10.00 (8.00, 13.00) | 8.00 (6.00, 11.00) | 0.022 |
Fertilized oocytes (2PN) | 6.00 (4.50, 9.00) | 6.00 (4.00, 7.75) | 0.292 |
No. of available embryos of Day 3 | 6.00 (4.00, 9.00) | 5.00 (4.00, 7.00) | 0.025 |
No. of blastocysts formed | 2.00 (0.00, 5.00) | 1.00 (0.00, 4.00) | 0.242 |
Rate of blastocyst formed (%) | 75.00 (50.00, 90.00) | 71.00 (33.00, 90.00) | 0.347 |
No. of high quality blastocysts | 0.00 (0.00, 1.00) | 0.00 (0.00, 0.00) | 0.056 |
Rate of high quality blastocysts (%) | 22.00 (0.00, 48.00) | 0.00 (0.00, 37.00) | 0.326 |
No. of embryos transferred | 1.83 ± 0.41 | 1.89 ± 0.31 | 0.263 |
Endometrial thickness (mm) | 10.78 ± 2.54 | 11.76 ± 2.75 | 0.017 |
Pregnancy rate (%) | 61.04 (47/77) | 68.00 (68/100) | 0.336 |
Clinical pregnancy rate (%) | 49.35 (38/77) | 53.00 (53/100) | 0.630 |
Miscarriage rate (%) | 31.58 (12/38) | 13.20 (7/53) | 0.033 |
Live birth rate (%) | 33.77 (26/77) | 46.00 (46/100) | 0.100 |