Table 6 Comparison of COS conditions and pregnancy outcomes in normal-BMI individuals
Variables | PCOS (n = 90) | Control (n = 166) | P-value |
|---|---|---|---|
Antral follicle count (AFC) | 24.00 (19.00, 29.25) | 14.00 (10.00, 17.25) | < 0.001 |
Infertility diagnosis | Â | Â | Â |
Primary infertility (%) | 64.44 (58/90) | 62.05 (103/166) | 0.705 |
Secondary infertility (%) | 33.56 (32/90) | 37.95 (63/166) | 0.705 |
ICSI cycles (%) | 14.44 (13/90) | 27.11 (45/166) | 0.021 |
Gn duration (days) | 10.00 (9.00, 11.50) | 11.00 (9.00, 12.00) | 0.041 |
Gonadotropin priming dosage (IU) | 150.00 (125.00, 150.00) | 168.75 (150.00, 225.00) | < 0.001 |
Gonadotropin dosage (IU) | 1500.00 (1350.00, 1800.00) | 2100.00 (1525.00, 2556.25) | < 0.001 |
E2 on hCG day (pg/ml) | 2546.29 (1744.25, 3653.75) | 2064.50 (1475.25, 2851.00) | 0.001 |
Retrieved oocytes | 10.00 (8.75, 14.00) | 11.00 (8.00, 14.00) | 0.671 |
No. of MII oocytes | 9.00 (6.00, 12.25) | 8.50 (6.00, 11.00) | 0.384 |
Fertilized oocytes (2PN) | 6.00 (4.00, 8.00) | 6.00 (4.00, 8.00) | 0.653 |
No. of available embryos of Day 3 | 6.00 (4.00, 9.00) | 5.50 (4.00, 7.25) | 0.077 |
No. of blastocysts formed | 2.00 (0.00, 5.25) | 2.00 (0.00, 4.00) | 0.507 |
Rate of blastocyst formed (%) | 77.00(50.00, 87.00) | 70.00 (50.00, 100.00) | 0.618 |
No. of high quality blastocysts | 0.00 (0.00, 1.00) | 0.00 (0.00, 1.00) | 0.017 |
Rate of high quality blastocysts (%) | 31.00 (0.00, 50.00) | 0.00 (0.00, 33.00) | 0.032 |
No. of embryos transferred | 1.91 ± 0.38 | 1.85 ± 0.39 | 0.227 |
Endometrial thickness (mm) | 10.31 ± 2.00 | 11.66 ± 2.66 | < 0.001 |
Pregnancy rate (%) | 64.44 (58/90) | 59.04 (98/166) | 0.397 |
Clinical pregnancy rate (%) | 46.67(42/90) | 51.81 (86/166) | 0.432 |
Miscarriage rate (%) | 16.67(7/42) | 9.30 (8/86) | 0.224 |
Live birth rate (%) | 38.89 (35/90) | 46.99 (78/166) | 0.213 |