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Table 1 Comparison of baseline characteristics and frozen-thawed embryo transfer cycle information of three groups before matching

From: Impact of different endometrial preparation protocols on pregnancy outcomes in patients at high risk for ovarian hyperstimulation syndrome: a propensity score matched retrospective cohort study

Characteristics

HRT (n = 1431)

NC (n = 212)

OS (n = 140)

P value

Age of the woman (years, mean ± SD)

29.64 ± 3.41

30.37 ± 3.33

29.86 ± 3.04

0.011

Age of the man (years, mean ± SD)

31.32 ± 3.81

31.78 ± 3.47

31.20 ± 3.71

0.217

BMI (kg/m 2,mean ± SD)

22.94 ± 3.51

21.27 ± 2.61

22.65 ± 3.29

< 0.001

Regular pattern of menstruation, n(%)

804 (56.18)

194 (91.51)

92 (65.71)

< 0.001

Type of infertility, n(%)

   

0.703

 Primary

528 (36.90)

82 (38.68)

56 (40.00)

 

 Secondary

903 (63.10)

130 (61.32)

84 (60.00)

 

Infertility factors, n(%)

   

< 0.001

 Female factor

954 (66.67)

99 (46.70)

87 (62.14)

 

 Male factor

227 (15.86)

69 (32.55)

30 (21.43)

 

 Bilateral factor

176 (12.30)

19 (8.96)

15 (10.71)

 

 Unexplained

74 (5.17)

25 (11.79)

8 (5.71)

 

Years of infertility (years, mean ± SD)

3.37 ± 2.10

3.46 ± 2.30

3.29 ± 2.19

0.732

Basal FSH(U/L, mean ± SD)

6.21 ± 1.67

6.63 ± 2.08

6.23 ± 1.75

0.012

Basal LH (U/L, mean ± SD)

7.09 ± 6.96

6.88 ± 11.38

5.77 ± 4.07

0.110

AFC (n, mean ± SD)

19.14 ± 6.18

16.20 ± 4.84

18.35 ± 6.37

< 0.001

Protocol in fresh cycle, n(%)

   

< 0.001

 Follicular-phase depot GnRH agonist

611 (42.70)

65 (30.66)

52 (37.14)

 

 Mid-luteal GnRH agonist

349 (24.39)

93 (43.87)

48 (34.29)

 

 Antagonist

471 (32.91)

54 (25.47)

40 (28.57)

 

Fertilization type, n(%)

   

0.798

 IVF

1187 (82.95)

159 (75.00)

113 (80.71)

 

 ICSI

244 (17.05)

53 (25.00)

27 (19.29)

 

Gn time of use (d, mean ± SD)

10.62 ± 2.31

10.28 ± 1.91

10.50 ± 2.14

0.226

Gn dosage (U, mean ± SD)

1935.89 ± 771.14

1854.54 ± 665.56

1919.45 ± 785.78

0.460

Trigger day E2 value (ng/L, mean ± SD)

5631.25 ± 2542.10

6063.53 ± 2648.25

5444.94 ± 2688.26

0.320

No. of oocyte retrieved(n, mean ± SD)

19.91 ± 6.16

19.40 ± 5.65

19.76 ± 6.03

0.428

Pre-transplantation endometrial thickness mm, n(%)

   

< 0.001

 < 8

37 (2.59)

7 (3.30)

3 (2.14)

 

 8–11

1021 (71.35)

96 (45.28)

51 (36.43)

 

 11–14

351 (24.53)

101 (47.64)

77 (55.00)

 

 >14

22 (1.54)

8 (3.77)

9 (6.43)

 

Triple-line endometrial pattern, n(%)

   

0.001

 A

237 (16.56)

52 (24.53)

39 (27.86)

 

 B

1054 (73.65)

141 (66.51)

84 (60.00)

 

 C

140 (9.78)

19 (8.96)

17 (12.14)

 

Type of embryo transferred, n(%)

   

0.734

Cleavage stage

170 (11.88)

27 (12.74)

14 (10.00)

 

Blastocyst stage

1261 (88.12)

185 (87.26)

126 (90.00)

 

No. of embryos transferred, n(%)

   

0.471

 1

1280 (89.45)

185 (87.26)

127 (90.71)

 

 2

151 (10.55)

27 (12.74)

13 (9.29)

 

Good quality embryo transferred, n(%)

1240 (86.65)

179 (84.43)

122 (87.14)

0.657

  1. Note: HRT: hormone replacement therapy; NC: natural cycle; OS: ovarian stimulation; SD: standard deviation; BMI: body mass index; FSH: follicle stimulating hormone; LH: luteinizing hormone; AFC: antral follicle count; IVF: in vitro fertilization; ICSI: intracytoplasmic sperm injection; Gn: gonadotropin; E2:estradiol; Triple-line endometrial pattern: pattern A (a triple-line pattern consisting of a central hyperechoic line surrounded by two hypoechoic layers), pattern B (an intermediate isoechogenic pattern with the same reflectivity as the surrounding myometrium and a poorly defined central echogenic line), and pattern C (homogenous, hyperechogenic endometrium).Good quality embryo: good quality cleavage-stage embryos were defined as those derived from normally zygote with an embryonic cell number of 7–9 and a fragmentation level of less than 10 on day 3 after fertilisation; high-quality blastocysts were defined as those with a score of better than 4CC
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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