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Table 1 Clinical characteristics for HELLP-group and non-HELLP-group

From: Development a nomogram for predicting HELLP syndrome in women complicated with gestational hypertension

Variables

non-HELLP-group

HELLP-group

P

(n = 607)

(n = 201)

Age(years)

32 (29–35)

33 (30–36.5)

0.011

Height(cm)

160 (158,164)

160 (156,162)

 < 0.001

Gravida

2 (1,3)

2 (1,3)

 < 0.001

Parity

0 (0,1)

0 (0,1)

0.001

Multipara(%)

214 (35.25%)

96 (47.76%)

0.002

ART(%)

84 (13.84%)

25 (12.44%)

0.645

Twin pregnancy(%)

46 (7.58%)

22 (10.95%)

0.147

Prepregnancy BMI(kg/m^2)

23.34 (21.12,25.84)

23.81 (20.89,27.37)

0.275

Prepartum BMI(kg/m^2)

29.08 (26.89,31.63)

28.76 (25.78,31.05)

0.149

Types of hypertension during pregnancy(%)

 Gestational hypertension

196 (32.29%)

15 (7.46%)

 < 0.001

 Preeclampsia

313 (51.57%)

152 (75.62%)

 < 0.001

 Eclampsia

1 (0.16%)

3(1.49%)

0.052

 Chronic hypertension with superimposed preeclampsia

79 (13.01%)

30(14.93%)

0.548

 Pregnancy complicated by chronic hypertension

18 (2.97%)

1(0.50%)

0.053

Blood pressure at admission(mmHg)

 Highest SBP

151 (142,162)

170(157.5,184.5)

 < 0.001

 lowest SBP

115 (108,121)

138(124,151)

 < 0.001

 SBP variability

36 (29,46)

31(17,46)

 < 0.001

 Highest DBP

96 (90,102)

107(99.5,117)

 < 0.001

 lowest DBP

69 (62,74)

85(75,97)

 < 0.001

 DBP variability

28 (22,34)

21(12,30)

 < 0.001

 Patients with neurological symptoms(%)

53 (8.73%)

47(23.38%)

 < 0.001

 Patients with other systemic symptoms(%)

21 (3.46%)

53(26.37%)

 < 0.001

 Urine protein(g/24 h)

0.66 (± 1.42)

3.70(± 4.60)

 < 0.001

Obstetric history(%)

 RSA

6 (0.99%)

3(1.49%)

0.705

 Inevitable abortion

59 (9.72%)

19(9.45%)

1.000

 Stillbirth

37 (6.10%)

9(4.48%)

0.482

 Pretern birth

30 (4.94%)

16(7.96%)

0.107

 Placental disorders

37 (6.10%)

10(4.98%)

0.604

 Immune dysfunction before pregnancy(%)

25 (4.12%)

4(1.99%)

0.209

Thyroid disorders(%)

 Hyperthyroidism

36 (5.93%)

14(6.97%)

0.170

 Hypothyroidism

10 (1.65%)

0(0.00%)

 Medication use during pregnancy(%)

 Prednisone

13 (2.14%)

6(2.99%)

1.000

 Aspirin

60 (9.88%)

16(7.96%)

0.475

 Low molecular weight heparin

44 (7.25%)

14 (6.97%)

1.000

 Hydroxychloroquine

10 (1.65%)

4 (1.99%)

0.745

  1. ART Assisted Reproductive Technology, BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, RSA Recurrent Spontaneous Abortion