Variables | non-HELLP-group | HELLP-group | P |
---|---|---|---|
(n = 607) | (n = 201) | ||
Age(years) | 32 (29–35) | 33 (30–36.5) | 0.011 |
Height(cm) | 160 (158,164) | 160 (156,162) | < 0.001 |
Gravida | 2 (1,3) | 2 (1,3) | < 0.001 |
Parity | 0 (0,1) | 0 (0,1) | 0.001 |
Multipara(%) | 214 (35.25%) | 96 (47.76%) | 0.002 |
ART(%) | 84 (13.84%) | 25 (12.44%) | 0.645 |
Twin pregnancy(%) | 46 (7.58%) | 22 (10.95%) | 0.147 |
Prepregnancy BMI(kg/m^2) | 23.34 (21.12,25.84) | 23.81 (20.89,27.37) | 0.275 |
Prepartum BMI(kg/m^2) | 29.08 (26.89,31.63) | 28.76 (25.78,31.05) | 0.149 |
Types of hypertension during pregnancy(%) | |||
Gestational hypertension | 196 (32.29%) | 15 (7.46%) | < 0.001 |
Preeclampsia | 313 (51.57%) | 152 (75.62%) | < 0.001 |
Eclampsia | 1 (0.16%) | 3(1.49%) | 0.052 |
Chronic hypertension with superimposed preeclampsia | 79 (13.01%) | 30(14.93%) | 0.548 |
Pregnancy complicated by chronic hypertension | 18 (2.97%) | 1(0.50%) | 0.053 |
Blood pressure at admission(mmHg) | |||
Highest SBP | 151 (142,162) | 170(157.5,184.5) | < 0.001 |
lowest SBP | 115 (108,121) | 138(124,151) | < 0.001 |
SBP variability | 36 (29,46) | 31(17,46) | < 0.001 |
Highest DBP | 96 (90,102) | 107(99.5,117) | < 0.001 |
lowest DBP | 69 (62,74) | 85(75,97) | < 0.001 |
DBP variability | 28 (22,34) | 21(12,30) | < 0.001 |
Patients with neurological symptoms(%) | 53 (8.73%) | 47(23.38%) | < 0.001 |
Patients with other systemic symptoms(%) | 21 (3.46%) | 53(26.37%) | < 0.001 |
Urine protein(g/24 h) | 0.66 (± 1.42) | 3.70(± 4.60) | < 0.001 |
Obstetric history(%) | |||
RSA | 6 (0.99%) | 3(1.49%) | 0.705 |
Inevitable abortion | 59 (9.72%) | 19(9.45%) | 1.000 |
Stillbirth | 37 (6.10%) | 9(4.48%) | 0.482 |
Pretern birth | 30 (4.94%) | 16(7.96%) | 0.107 |
Placental disorders | 37 (6.10%) | 10(4.98%) | 0.604 |
Immune dysfunction before pregnancy(%) | 25 (4.12%) | 4(1.99%) | 0.209 |
Thyroid disorders(%) | |||
Hyperthyroidism | 36 (5.93%) | 14(6.97%) | 0.170 |
Hypothyroidism | 10 (1.65%) | 0(0.00%) | |
Medication use during pregnancy(%) | |||
Prednisone | 13 (2.14%) | 6(2.99%) | 1.000 |
Aspirin | 60 (9.88%) | 16(7.96%) | 0.475 |
Low molecular weight heparin | 44 (7.25%) | 14 (6.97%) | 1.000 |
Hydroxychloroquine | 10 (1.65%) | 4 (1.99%) | 0.745 |