Associations of maternal serum transthyretin concentration with pregnancy and birth outcomes

Table 4 Presented the adjusted associations between maternal TTR levels and fetal outcomes, including preterm birth, SGA and LGA, highlighting their prevalence rates across difference TTR levels categories. In this study, 309 fetuses (4.7%) were delivered preterm. Additionally, 446 fetuses (6.8%) were SGA, while 560 fetuses (8.5%) were LGA. When maternal TTR concentration was analyzed both as a categorical variable by quartiles and as a continuous variable, a statistically significant association was observed with preterm delivery (adjusted OR 0.986 [95% CI 0.983–0.989]; P < 0.001). There were no significant associations observed between maternal TTR concentration and the risks of SGA or LGA (all P > 0.05)

Table 4. Adjusted associations of maternal TTR concentration in pregnancy with fetal complications.
CI, confidence interval; OR, odds ratio; TTR, transthyretin; SGA small for gestational age; LGA, large for gestational age.
*All models adjusted for child’s sex, maternal age, pre-pregnancy BMI, marital status, education level, parity, hepatitis virus carrying status, chronic hypertension and pregestational diabetes.
**All models adjusted for child’s sex, maternal age, pre-pregnancy BMI, marital status, education level, parity, gestational age, hepatitis virus carrying status, chronic hypertension and pregestational diabetes

ISSN: 1471-2393