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Table 4 Differences in breastfeeding and non-breastfeeding mothers with JIA six weeks postpartum

From: Breastfeeding in women with juvenile idiopathic arthritis: results from a Norwegian quality register

 

N

Breastfeeding

N = 248

N

Non-breastfeeding

N = 42

p-valuea

Patient background

     

Age (years), mean (SD)

248

29.9 (4.2)

42

28.7 (5.7)

0.119

 Age > 35 years, n (%)

 

22 (8.9)

 

6 (14.3)

0.264

BMI (kg/m2), mean (SD)

240

24.9 (4.5)

40

25.2 (3.3)

0.662

 Overweight, n (%)

 

104 (43.3)

 

16 (40.0)

1.000

Working full time or part time, n (%)

247

33 (13.4)

39

1 (2.6)

0.061

Regular physical activity, n (%)b

169

73 (43.2)

28

12 (42.9)

1.000

Cigarette/Snuff use, n (%)

241

11 (4.6)

37

5 (13.5)

0.046

Education level, n (%)c

243

 

41

 

< 0.001

 Low

 

5 (2.1)

 

4 (9.8)

 

 Intermediate

 

47 (19.3)

 

17 (41.5)

 High

 

191 (78.6)

 

20 (48.8)

Pregnancy and labour

     

Pregnancy duration (weeks), mean (SD)

248

39.5 (1.6)

41

37.9 (3.2)

0.004

 Premature birth, n (%)d

 

12 (4.8)

 

9 (22.0)

< 0.001

Birth weight (grams), mean (SD)

247

3511.6 (501.3)

42

3175 (793.3)

0.011

CS, n (%)

246

51 (20.7)

42

19 (45.2)

0.007

 Emergency CS, n (%)

 

38 (15.4)

 

13 (31.0)

 

Complications, n (%)e

236

7 (3.0)

41

4 (9.8)

0.063

Disease related characteristics

     

Disease duration (years), mean (SD)

217

22.1 (16.4)

38

17.7 (9.2)

0.087

CRP(mg/L), mean (SD)

193

6.1 (11.6)

36

4.2 (8.1)

0.067

 CRP > 5 mg/L, n (%)

 

60 (31.1)

 

5 (13.9)

0.057

DAS-28-CRP-3, mean (SD)

171

2.6 (2.3)

32

2.5 (1.1)

0.64

Remission (DAS-28-CRP-3 < 2.6), n (%)

 

110 (64.3)

 

22 (68.8)

0.78

Active disease (DAS-28-CRP-3 ≥ 2.6), n (%)

 

61 (35.7)

 

10 (31.3)

 

VAS score (mm), mean (SD)

     

 Pain

190

24.3 (23.8)

34

37.9 (24.9)

0.002

 Fatigue

 

25.4 (24.4)

 

39.5 (31.9)

0.030

 Total

187

191

28.9 (27.3)

33

34

38.4 (26.0)

0.023

Medications

     

csDMARDs, n (%)

247

52 (21.1)

42

12 (28.6)f

0.021

 Hydroxychloroquine, n (%)

 

14 (5.7)

 

3 (7.1)

 

 Methotrexate, n (%)

 

2 (0.81)

 

4 (9.5)

 Sulfasalazine, n (%)

 

36 (14.6)

 

6 (14.3)

bDMARDs, n (%)

248

 

42

 

0.686

 TNF inhibitor, n (%)

 

61 (24.6)

 

11 (26.2)

 

 IL-6 inhibitor, n (%)

 

4 (1.6)

 

1 (2.4)

Corticosteroids, n (%)

247

26 (10.5)

42

4 (9.5)

1.000

  1. a Two-sided p-value ≤ 0.05 with no adjustment made for multiple comparisons. Group comparisons were performed using Independent samples t-test for continuous, normally distributed variables. For continuous, ordinal (non-normally distributed) variables, the Mann Whitney U test was performed. Chi Square test was performed for categorical variables, and Fisher´s exact test for small-sample sizes
  2. b Aerobic exercise for a minimum of 30 min at least once a month
  3. c Education level: low = elementary school, medium = high school/vocational education, education, high = college/university
  4. d Birth before gestational week 37
  5. e Preeclampsia, eclampsia, HELLP-syndrome
  6. f One woman registered was using both hydroxychloroquine and methotrexate simultaneously