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Table 5 Differences in breastfeeding and non-breastfeeding mothers with JIA six months postpartum

From: Breastfeeding in women with juvenile idiopathic arthritis: results from a Norwegian quality register

 

N

Breastfeeding

N = 166

N

Non-breastfeeding n = 71

p-valuea

Patient background

     

Age (years), mean (SD)

166

30.0 (4.1)

71

28.8 (4.9)

0.077

 Age > 35 years, n (%)

 

14 (8.4)

 

8 (11.3)

0.657

BMI (kg/m2), mean (SD)

152

25.9 (15.3)

63

25.6 (4.7)

0.135

 Overweight ≥ 25 mg/m2), n (%)

 

58 (38.2)

 

29 (46.0)

0.614

Working full time or part time, n (%)

164

14 (8.5)

69

8 (11.6)

0.629

Regular physical activity, n (%)b

120

72 (60.0)

46

29 (63.0)

0.856

Cigarette/Snuff use, n (%)

160

7 (4.4)

66

11 (16.7)

0.005

Education level, n (%)c

162

 

70

 

< 0.001

 Low

 

3 (1.9)

 

2 (2.9)

 

 Intermediate

 

26 (16.0)

 

29 (41.4)

 High

 

133 (82.1)

 

39 (55.7)

Disease related characteristics

     

CRP (mg/L), mean (SD)

137

4.5 (7.4)

53

5.0 (5.9)

0.128

 CRP value > 5 mg/L, n (%)

 

30 (21.9)

 

18 (34.0)

0.126

DAS-28-CRP-3, mean (SD)

121

2.7 (2.7)

52

2.5 (0.9)

0.412

 Remission (DAS-28-CRP-3 < 2.6), n (%)

 

76 (62.8)

 

29 (55.8)

0.484

 Active disease (DAS-28-CRP-3 ≥ 2.6), n (%)

 

45 (37.2)

 

23 (44.2)

0.484

VAS-score (mm), mean (SD)

     

 Pain

130

26.3 (23.4)

53

29.9 (25.1)

0.475

 Fatigue

131

30.5 (28.6)

 

42.8 (31.6)

0.028

 Total

128

28.5 (25.4)

48

55

29.6 (25.7)

0.839

Medications

     

csDMARDs, n (%)

162

44 (27.2)

70

21 (29.6)d

0.002

 Hydroxychloroquine, n (%)

 

9 (5.6)

 

7 (10.0)

 

 Methotrexate, n (%)

 

4 (2.5)

 

10 (14.3)

 Sulfasalazine, n (%)

 

31 (19.1)

 

5 (7.1)

bDMARDs, n (%)

163

 

70

 

0.102

 TNF inhibitor, n (%)

 

71 (43.6)

 

33 (47.1)

 

 IL-6 inhibitor, n (%)

 

1 (0.61)

 

3 (4.3)

Corticosteroids, n (%)

164

21 (12.8)

70

10 (14.3)

0.924

  1. a Two-sided p-value ≤ 0.05 with no adjustment made for multiple comparisons. Group comparisons were performed using Independent samples t-test for continuous, normally distributed variables. For continuous, ordinal (non-normally distributed) variables, the Mann Whitney U test was performed. Chi Square test was
  2. b performed for categorical variables, and Fisher´s exact test for small-sample sizes
  3. c Aerobic exercise for a minimum of 30 min at least once a month
  4. d Education level: low = elementary school, medium = high school/vocational, education, high = college/university
  5. e One woman was registered using both hydroxychloroquine and methotrexate simultaneously