Table 1 Comparisons of the baseline variables between the study and control group (singleton)
From: Pregnancy outcomes among women near the end of reproductive age
Study Group (age ≥ 45 years) N: 121 | Control Group (age 20–34 years) N: 51,315 | P | RR (95% CI) | |
|---|---|---|---|---|
Age | 45.97 ± 1.38 | 26.93 ± 4.06 | < 0.001 | |
Nulliparous | 24 (19.8%) | 28,516 (55.6%) | < 0.001 | |
Multiparous | 97 (80.2%) | 22,779 (44.4%) | < 0.001 | |
Number of antenatal visits | 5.8 ± 4.2 | 8.1 ± 4.3 | < 0.001 | |
Previous cesarean birth | 11 (9.1%) | 3,371 (6.6%) | 0.264 | 1.38 (0.79–2.43) |
Medical diseases (combined) | 37 (30.6%) | 8,438 (16.4%) | < 0.001 | 1.86 (1.42–2.43) |
Iron deficiency | 1 (0.8%) | 850 (1.7%) | 0.475 | 0.50 (0.07–3.51) |
Myoma uteri | 3 (2.5%) | 338 (0.7%) | 0.014 | 3.76 (1.23–11.57) |
Epilepsy | 0 (0.0%) | 123 (0.2%) | 0.590 | - |
Condyloma accuminata | 0 (0.0%) | 162 (0.3%) | 0.536 | - |
Syphilis | 0 (0.0%) | 52 (0.1%) | 0.726 | - |
Asthma | 2 (1.7%) | 553 (1.1%) | 0.541 | 1.53 (0.39–6.08) |
Chronic hypertension | 8 (6.6%) | 849 (1.7%) | < 0.001 | 4.00 (2.04–7.83) |
Pregestational DM | 3 (2.9%) | 232 (0.5%) | < 0.001 | 5.96 (1.94–18.29) |
HBV carrier | 7 (5.8%) | 2,929 (5.7%) | 0.971 | 1.01 (0.49–2.08) |
HIV infection | 1 (0.8%) | 833 (1.6%) | 0.488 | 0.51 (0.07–3.59) |
Heart disease | 2 (1.7%) | 454 (0.9%) | 0.368 | 1.87 (0.47–7.40) |
SLE | 0 (0.0%) | 256 (0.5%) | 0.436 | - |
Thalassemia disease | 0 (0.0%) | 320 (0.6%) | 0.384 | - |
Thyrotoxicosis | 2 (1.7%) | 478 (0.9%) | 0.410 | 1.77 (0.45–7.03) |
Fetal trisomy | 11 (9.1%) | 61 (0.1%) | < 0.001 | 76.47 (41.27–141.70) |
Miscarriage | 10/119 (8.4%) | 389 (0.8%) | < 0.001 | 11.07 (6.07–20.21) |