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Table 4 Crude and adjusted odd ratios for the risk of preeclampsia, preterm birth, fetal growth restriction, and low birth weight derived from logistic regression analysis

From: Pregnancy outcomes among women near the end of reproductive age

Potential risk factors

Univariate analysis

Multivariate analysis

P-value

Crude odds ratio (95% CI)

P-value

Adjusted odds ratio (95% CI)

Preeclampsia

Extremely-advanced age

< 0.001

3.36 (1.95–5.78)

< 0.001

4.24 (2.35–7.66)

Socio-economic status (ref: low)

0.409

1.04 (0.95–1.14)

0.837

0.99 (0.90–1.09)

Pre-pregnancy BMI (Kg/m2)

0.741

1.00 (0.99–1.01)

0.615

1.00 (0.99–1.01)

Parity (ref: 0)

0.172

0.96 (0.91–1.02)

0.009

0.91 (0.85–0.98)

Number of antenatal care visits

0.117

0.99 (0.98-1.00)

0.088

0.99 (0.98-1.00)

Smoking (ref: no)

0.930

0.98 (0.62–1.53)

0.822

0.94 (0.56–1.59)

Preterm birth

Extremely-advanced age

< 0.001

3.50 (2.26–5.42)

< 0.001

3.35 (2.00-5.61)

Socio-economic status (ref: low)

< 0.001

0.86 (0.80–0.91)

0.486

0.98 (0.91–1.05)

Pre-pregnancy BMI (Kg/m2)

0.029

0.99 (0.99-1.00)

0.036

0.99 (0.98-1.00)

Parity (ref: 0)

< 0.001

1.14 (1.10–1.18)

0.373

0.98 (0.94–1.03)

Number of antenatal care visits

< 0.001

0.83 (0.83–0.84)

0.000

0.83 (0.83–0.84)

Smoking (ref: no)

0.032

1.35 (1.03–1.78)

0.496

1.12 (0.80–1.58)

Fetal growth restriction

Extremely-advanced age

0.001

2.65 (1.52–4.62)

< 0.001

3.64 (1.93–6.86)

Socio-economic status (ref: low)

< 0.001

0.83 (0.76–0.90)

< 0.001

0.82 (0.75–0.90)

Pre-pregnancy BMI (Kg/m2)

0.014

0.99 (0.98-1.00)

0.007

0.99 (0.98-1.00)

Parity (ref: 0)

< 0.001

0.76 (0.72–0.80)

< 0.001

0.69 (0.65–0.74)

Number of antenatal care visits

< 0.001

0.95 (0.94–0.96)

< 0.001

0.95 (0.94–0.96)

Smoking (ref: no)

0.276

1.23 (0.85–1.79)

0.167

1.34 (0.88–2.03)

Low birth weight

Extremely-advanced age

< 0.001

3.86 (2.51–5.94)

< 0.001

4.67 (2.85–7.65)

Socio-economic status (ref: low)

0.010

0.92 (0.87–0.98)

0.468

0.98 (0.91–1.04)

Pre-pregnancy BMI (Kg/m2)

0.018

0.99 (0.98-1.00)

0.012

0.99 (0.98-1.00)

Parity (ref: 0)

< 0.001

0.93 (0.89–0.96)

< 0.001

0.81 (0.77–0.85)

Number of antenatal care visits

< 0.001

0.89 (0.88–0.89)

< 0.001

0.88 (0.88–0.89)

Smoking (ref: no)

0.069

1.30 (0.98–1.71)

0.137

1.28 (0.93–1.77)

  1. (BMI: body mass index)