| Belimumab | Control | P value | |
---|---|---|---|---|
Number of live births (%) | 45(88.23) | 36(70.59) | 0.048 | |
Number of abortions (%) | 6(11.77) | 15(29.41) | 0.048 | |
Gestational age of abortion (weeks, mean ± SD) | 7.1 ± 1.3 | 7.3 ± 1.2 | 0.421 | |
Neonate Apgar score (mean ± SD) | 1 min | 9.5 ± 0.6 | 9.6 ± 0.6 | 0.402 |
5 min | 9.8 ± 0.3 | 9.9 ± 0.4 | 0.157 | |
Neonate weight (g, mean ± SD) | 3059 ± 236 | 3118 ± 223 | 0.197 | |
B cell percentage at 12 weeks | 17.57 ± 0.40 | 21.23 ± 1.37 | < 0.0001 | |
B cell count at 12 weeks | 512.60 ± 26.67 | 607.82 ± 52.43 | < 0.0001 | |
Therapy side effects | Rash | 1 | 1 | 1.000 |
Hypertension | 1 | 4 | 0.362 | |
Maternal IgG at 12 weeks (g/L, mean ± SD) | 9.4 ± 0.8 | 9.5 ± 0.7 | 0.503 | |
Neonatal white blood cell counts (×109/L, mean ± SD) | 16.8 ± 1.8 | 17.5 ± 2.0 | 0.066 |