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Table 2 Comparison of pregnancy and delivery data between the two groups

From: Role of belimumab in recurrent spontaneous abortions amongst patients with lymphocyte dysfunction: a retrospective case-control study

 

Belimumab

Control

P value

Number of live births (%)

45(88.23)

36(70.59)

0.048

Number of abortions (%)

6(11.77)

15(29.41)

0.048

Gestational age of abortion (weeks, mean ± SD)

7.1 ± 1.3

7.3 ± 1.2

0.421

Neonate Apgar score (mean ± SD)

1 min

9.5 ± 0.6

9.6 ± 0.6

0.402

5 min

9.8 ± 0.3

9.9 ± 0.4

0.157

Neonate weight (g, mean ± SD)

3059 ± 236

3118 ± 223

0.197

B cell percentage at 12 weeks

17.57 ± 0.40

21.23 ± 1.37

< 0.0001

B cell count at 12 weeks

512.60 ± 26.67

607.82 ± 52.43

< 0.0001

Therapy side effects

Rash

1

1

1.000

Hypertension

1

4

0.362

Maternal IgG at 12 weeks (g/L, mean ± SD)

9.4 ± 0.8

9.5 ± 0.7

0.503

Neonatal white blood cell counts (×109/L, mean ± SD)

16.8 ± 1.8

17.5 ± 2.0

0.066