Skip to main content

Table 3 Amniotic and maternal laboratory findings of participants

From: Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study

Variables

Non-DS pregnancies

(n = 37)

DS pregnancies

(n = 28)

P value

NQO1-AS (ng/ml)

505.62 ± 358.17

924.84 ± 475.94

< 0.001

NQO1-MS (ng/ml)

394.87 ± 344.86

716.216 ± 242.91

< 0.001

NFKB-AS (ng/ml)

2.51 ± 0.86

2.57 ± 0.75

0.783

NFKB-MS (ng/ml)

2.21 ± 1.45

2.80 ± 1.89

0.178

NRF2-AS (ng/ml)

6.47 ± 5.53

3.77 ± 4.20

0.029

NRF2-MS (ng/ml)

14.46 ± 16.53

7.54 ± 5.68

0.022

CSE-AS (ng/ml)

10.13 ± 7.89

12.21 ± 7.40

0.280

CSE-MS (ng/ml)

9.17 ± 11.02

16.68 ± 17.07

0.049

  1. AS: amniotic serum, MS: maternal serum, NQO1: NAD(P)H dehydrogenase [quinone] 1, NRF2: nuclear factor erythroid 2-related factor 2, NFKB: nuclear factor-kappa B, CSE: cystathionine-γ-lyase, DS: Down syndrome