Table 5 Diagnostic performance of NRF2-AS and NRF2-MS for DS prediction
From: Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study
Parameter | NRF2-AS | NRF2-MS |
|---|---|---|
AUC (95% CI) | 0.48 (0.39–0.57) | 0.45 (0.36–0.54) |
Cut-off value (ng/ml) | 5.0 | 10.0 |
Sensitivity (%) | 45 | 42 |
Specificity (%) | 52 | 48 |
Positive Predictive Value (%) | 48 | 45 |
Negative Predictive Value (%) | 49 | 46 |
Accuracy (%) | 47 | 44 |