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Table 6 Diagnostic performance of CSE-MS for DS prediction

From: Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study

Parameter

CSE-MS

AUC (95% CI)

0.62 (0.53–0.71)

Cut-off value (ng/ml)

12.5

Sensitivity (%)

65

Specificity (%)

60

Positive Predictive Value (%)

62

Negative Predictive Value (%)

63

Accuracy (%)

62

  1. CSE: cystathionine-γ-lyase, MS: maternal serum, CI: Confidence Interval, DS: Down syndrome, AUC: Area Under the Curve