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Table 2 HBV serologic markers in infants with different delivery modes and feeding patterns

From: Elective cesarean section and bottle-feeding do not reduce infection of hepatitis B in infants of high viremic mothers: a retrospective study

Variable

Vaginal delivery + breastfed (n = 157)

ECS + breastfed

(n = 127)

Vaginal delivery + bottle-fed (n = 91)

ECS + bottle-fed (n = 87)

Statistical Analysis

P

HBsAg-positive, n (rate, %)

4 (2.5)

5 (3.9)

1 (1.1)

1 (1.1)

χ2  = 2.090

0.538

Anti-HBs ≥ 10 mIU/ml, n (rate, %)

152 (96.8)

121 (95.3)

89 (97.8)

85 (97.7)

χ2  = 1.255

0.762

Anti-HBs level (mIU/ml), n (proportion, %)

      

 ≥ 1000

108 (68.8)

83 (65.4)

58 (63.7)

53 (60.9)

χ2  = 14.266

0.218

 100-999.9

40 (25.5)

32 (25.2)

21 (23.1)

22 (25.3)

 10-99.9

4 (2.5)

6 (4.7)

10 (11.0)

10 (11.5)

 1-9.9

1 (0.6)

1 (0.8)

1 (1.1)

1 (1.1)

 < 1

4 (2.5)*

5 (3.9)*

1 (1.1)*

1 (1.1)*

Anti-HBs level (mIU/ml)†

      

 ≥ 1000‡

≥ 1000

≥ 1000

≥ 1000

≥ 1000

N/A

N/A

 100-999.9

367.2 (108.3–967.8)

417.3 (100.8–967.5)

379.8 (102.8–892.0)

345.0 (114.2–871.1)

Z = 1.047

0.790

 10-99.9

41.5 (22.9–53.2)

43.9 (16.0–98.2)

57.8 (21.1–99.2)

56.3 (10.6–95.6)

Z = 3.402

0.334

 1-9.9

7.92

1.23

9.45

5.75

N/A

N/A

  1. Abbreviations: ECS, elective cesarean section; HBsAg, hepatitis B surface antigen; anti-HBs, antibody against HBsAg; N/A, not applicable.
  2. *These infants were positive for HBsAg.
  3. †Anti-HBs titer was expressed in GMC (geometric mean concentration) followed by minimum and maximum values.
  4. ‡Since anti-HBs was beyond the upper detection limit (1000 mIU/ml), the GMC and range of anti-HBs were not calculated