Fig. 2

Global burden of CBDs for both sexes in 204 countries and territories. (A) Prevalence in 2021; EAPC of prevalence rates between 1990 and 2021. (B) Death rate in 2021; EAPC of death rate attributable to CBDs between 1990 and 2021. (C) DALY rate in 2021; EAPC of DALY rate attributable to CBDs between 1990 and 2021. CBDs, congenital birth defects; EAPC, estimated annual percentage change; DALY, disability-adjusted life year