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Table 5 Adjusted univariate generalised linear model of sleep quality and inflammatory biomarkers

From: Sleeping for two: a cross-sectional study on associations between objectively measured sleep during early to mid-pregnancy and maternal and fetal outcomes and inflammatory biomarker profiles

 

Good sleep

N = 728 (50.4%)

Intermediate sleep

N= 471 (32.6%)

Poor sleep

N = 245 (17.0%)

Variable N = 407

N

Ref

N

βa (95% CI)

Std error

t

p

N

βa (95% CI)

Std error

t

p

SRC

196

 

146

-0.34 (-0.54, -0.14)*

0.10

-3.36

< 0.001

65

-0.40 (-0.66, -0.14)*

0.13

-3.00

0.003

CD40L

196

 

146

-0.31 (-0.52, -0.10)*

0.11

-2.93

0.004

65

-0.40 (-0.67, -0.12)*

0.14

-2.82

0.005

STK4

196

 

146

-0.29 (-0.50, -0.08)*

0.11

-2.69

0.007

65

-0.37 (-0.65, -0.10)*

0.14

-2.66

0.008

THPO

196

 

146

-0.05 (-0.12, 0.03)

0.04

-1.28

0.201

65

0.09 (-0.00, 0.19)

0.05

1.92

0.055

DECR1

196

 

146

-0.35 (-0.55, -0.15)*

0.10

-3.49

< 0.001

65

-0.31 (-0.57, -0.05)*

0.13

-2.37

0.018

ITGB1BP2

196

 

146

-0.34 (-0.57, -0.11)*

0.12

-2.93

0.004

65

-0.37 (-0.67, -0.07)*

0.15

-2.41

0.016

NEMO

196

 

146

-0.25 (-0.43, -0.08)*

0.09

-2.86

0.004

65

-0.29 (-0.52, -0.06)*

0.12

-2.49

0.013

HSP27

196

 

146

-0.13 (-0.23, -0.03)*

0.05

-2.54

0.011

65

-0.14 (-0.28, -0.01)*

0.07

-2.10

0.037

IL27

196

 

146

-0.09 (-0.16, -0.03)*

0.03

-2.73

0.007

65

-0.03 (-0.11, 0.06)

0.05

-0.58

0.566

  1. N = number, Ref = reference group, βa = adjusted beta coefficient, Std = standard, t = t-value, p = p-value, SCR = Proto-oncogene tyrosine-protein kinase, CD40L = CD40 ligand, STK4 = Serine/threonine-protein kinase 4, THPO = thrombopoietin, DECR1 = 2,4-dienoyl-CoA reductase 1, ITGB1BP2 = Integrin Subunit Beta 1 Binding Protein 2, NEMO = nuclear factor κB (NF-κB) essential modulator, HSP27 = Heat shock protein-27, IL27 = Interleukin 27. Variables adjusted for: Country of birth, BMI at first antenatal visit, Pre-pregnancy diabetes and Parity
  2. *Significantly different from good sleep
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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