Table 2 Impact of uterine niche on ART
Study | Design | n | Artificial reproduction technique | Result |
|---|---|---|---|---|
Zhang 2022 [38] | Retrospective cohort study | 1122 | In vitro fertilized frozen-thawed embryo transfer | The clinical pregnancy and live birth rates were decreased in the CSD group compared with the VD and CD groups. |
Lawrenz 2019 [14] | Observational and exploratory clinical study (No strict cohort design) | 495 | Frozen embryo transfer | No significant differences in the reproductive outcome after FET were found between the patients with and without an Isthmocele when ICF was excluded before the embryo transfer procedure. |
Mensi 2023 [2] | Retrospective cohort study | 114 | IVF | The clinical pregnancy rate and live birth rate were significantly lower among women with CSD. |
Diao 2021 [39] | Retrospective cohort study | 834 | IVF/ICSI | The live birth rate and mean implantation rate in the CSD group were significantly lower than those in the VD and CD groups. |
Yao 2022 [40] | Retrospective cohort study | 2449 | IVF/ICSI | Compared with women without niches, women with niches had a reduced live birth rate and implantation rate. |
Cohen 2023 [41] | Retrospective case-control study | 86 | Embryo transfer | Patients undergoing fertility treatments, whether diagnosed with a uterine niche before conception or not, exhibited similar live birth rates. |