Fig. 6

tsRNA1 affects HTR-8/SVneo cell function by increasing DNA methylation. (A) Heatmap of differentially methylated genes. (B) TET1 and DNMT1 mRNA changes (transcriptome data). (C-D) RT-qPCR validation of TET1/DNMT1. (E) Model of tsRNA1-induced hypermethylation. Note: Partial content created in BioRender. Wu, Y. (2025) https://BioRender.com/o00f307