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Table 2 Clinical characteristics of the individuals included in this study

From: Maternal plasma extracellular vesicles tsRNA as potential biomarkers for assessing preterm labor risk

 

Overall (n = 83)

CTRLa(n = 38)

PTLb (n = 45)

χ2

P

Gestational age (weeks)

 

38.8 ± 3.1

30.9 ± 2.6

−15.23 (t test)

< 0.001*

Drug

   

0.009

0.923

yes

25 (34.72)

13 (18.06)

12 (16.67)

  

no

47 (65.28)

25 (34.72)

22 (30.56)

  

Pregnancy complications

   

1.241

0.538

no

76(92.68)

35 (42.68)

41(50.00)

  

Gestational diabetes

5 (6.10)

3 (3.66)

2(2.44)

  

preeclampsia

1 (1.22)

0 (0.00)

1(1.22)

  

delivery

   

15.02

<0.0005*

natural labour

72 (86.75)

27 (32.53)

45 (54.22)

  

caesarean birth

10 (12.05)

10 (12.05)

0 (0.00)

  

forceps delivery

1 (1.20)

1 (1.20)

0 (0.00)

  

premature rupture of membranes

   

14.72

<0.0001*

yes

30 (38.46)

6 (7.69)

24 (30.77)

  

no

48 (61.53)

24 (39.74)

17 (21.79)

  

Fetal weight

   

39.23

<0.0001*

<2000 g

27 (34.62)

0 (0.00)

27 (34.62)

  

>2000 g

51 (65.39)

38 (48.72)

13 (16.67)

  

Placenta weight

   

48.05

<0.0001*

<500 g

35 (54.05)

2 (2.70)

33 (40.54)

  

>500 g

38 (45.95)

33 (51.35)

5 (5.41)

  

Amnionitis

   

13.76

0.0002*

yes

21 (21.88)

4 (3.13)

17 (18.75)

  

no

49 (78.13)

33 (53.13)

16 (25.00)

  

First pregnancy

   

0.050

0.823

yes

40 (42.22)

18 (15.56)

22 (26.67)

  

no

40 (57.78)

19 (26.67)

21 (31.11)

  

Abortion

   

2.967

0.227

no

48 (56.47)

20 (23.53)

28(32.94)

  

artificial abortion

21 (24.71)

13 (15.29)

8 (9.42)

  

spontaneous abortion

16 (18.82)

6 (7.06)

10 (11.76)

  

Paternal smoker

   

0.312

0.576

yes

27 (40.00)

11 (17.78)

16 (22.22)

  

no

55 (60.00)

26 (24.44)

29 (35.56)

  

Exposure to smoke

     

yes

4(7.27)

0(0.00)

4(7.27)

 

0.044*

no

51(92.73)

29(52.73)

22(40.00)

  

Maternal education

   

1.864

0.172

≤bachelor

59 (70.45)

25 (29.55)

34 (13.64)

  

≥master

20 (29.55)

12 (40.91)

8 (15.91)

  

Paternal education

   

0.601

0.438

≤bachelor

30 (68.18)

15 (34.09)

15 (34.09)

  

≥master

14 (31.82)

4 (9.09)

10 (22.73)

  

Maternal income

   

1.253

0.263

<9000

52 (63.64)

22 (25.00)

30 (38.64)

  

>9000

27 (36.36)

15 (18.18)

12 (18.18)

  

Paternal income

   

0.612

0.434

<9000

27 (29.55)

11 (11.36)

16 (18.18)

  

>9000

52 (70.45)

26 (31.82)

26 (38.64)

  

Live with elders

   

0.152

0.697

yes

43 (47.73)

21 (20.45)

22 (27.27)

  

no

36 (52.27)

16 (22.73)

20 (29.55)

  

Area of house (m2)

   

5.639

0.018*

<100

39 (54.55)

13 (31.82)

26 (22.73)

  

>100

40 (45.45)

24 (11.36)

16 (34.09)

  

Early pregnancy nocturia

    

0.022*

<3

6 (17.14)

6 (17.14)

0 (0.00)

  

≥ 3

29 (82.86)

13 (37.14)

16 (45.71)

  
  1. aCTRL: Control group (term deliveries, gestational age ≥ 37 weeks)
  2. bPTL: Spontaneous preterm labor group (delivery between 20 + 0 and 36 + 6 weeks of gestation, confirmed by first-trimester ultrasound, with regular uterine contractions and cervical dilation ≥ 4 cm, excluding iatrogenic causes)
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BMC Pregnancy and Childbirth

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