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Estimated effect of teenage pregnancy on adverse birth outcome in Sub-Saharan African countries: propensity score matching analysis of recent demographic and health survey data
BMC Pregnancy and Childbirth volume 25, Article number: 442 (2025)
Abstract
Introduction
Globally adverse birth outcome is being a series public health problem. As studies showed, even though the etiologies are multifactorial, extreme age pregnancies have more risk for adverse birth outcome. This study determines the estimated effect of teenage pregnancy on adverse birth outcome.
Method
The study analyzed data from the most recent Demographic and Health Surveys (DHS) data. Propensity score matching (PSM) analysis was employed by using age as treatment variable, teenager as treated and non-teenagers as control group and weighted sample of 45,790 (non-teenagers = 41,769 and teenagers = 4,021). The outcome variable; adverse birth outcome was categorized as “Yes” if a woman had either preterm birth, still birth, low birth weight or macrosomia in her recent birth and “No” otherwise. Covariates that had significant association with the treatment and outcome variables were considered for PSM analysis. After testing of each matching techniques (nearest neighbor, kernel and radius), the nearest neighbor (10) approach produced better covariate balance and selected as the best matching algorism for our analysis. Finally, the effect of teenage pregnancy on adverse birth outcome was measured and reported as average treatment effect on the treated (ATT) and the quality of matching and sensitivity to hidden bias was assed by t-statistics significance level and Mantel–Haenszel statistic respectively.
Results
This study found that around one in ten (8.7%) of the women had pregnancy between the age of 15 and 19 years. The magnitude of adverse birth outcome among teenagers and non-teenagers was also 45.4% and 39.9% respectively. Teenage pregnancy contributed to a 4.7% increasing adverse birth outcome (ATT = 4.7%). Similarly, the Average Treatment Effect on Untreated (ATU) was 4.8%.
Conclusion
This study revealed that around one in teen women had pregnancy between the age of 15 and 19 years and teenage pregnancy had more risk of having adverse birth outcomes as compared to non-teenagers. Thus, we recommend to policy makers and implementers to design policies and strategies to improve teenagers’ access to prenatal care, family planning, and sexual education, awareness of creation on teenage pregnancy risks.
Introduction
Adverse birth outcome is defined as a low birth weight (LBW) (birth weight < 2500gram), macrosomia (birth weight > 4000 gram), stillbirth (fetal death at or after 7 months of gestation and before second stage of labor), and preterm birth (less than 37 weeks at birth) [1, 2]. Globally, the burden of adverse birth outcomes is being a series public health problem. Over the world an estimated 13 million, 46 million, and 2.6 million pregnancies end in preterm birth, abortion, and stillbirth annually, respectively. Moreover, around 20% and 15% of all births are LBWs and macrosomia respectively [2, 3].
Although the etiologies of adverse birth outcomes are multifactorial and not completely understood yet, studies showed that being on the extreme age (below 20 years and above 40 years) group has significant attribution [4,5,6]. Moreover, teenage pregnant faced with the simultaneous challenges of pregnancy and parenting while navigating the developmental tasks of adolescence which increases their risk for social and psychological health problems [7].
Teenage pregnancy refers to either intended or unintended pregnancy occurred within the age below 19 years. It is a major public health concern worldwide. The World Health Organization has estimated that every year approximately 17 million females aged below 19 years give birth [8, 9]. The magnitude of teenage pregnancy varies from 0.29% in south Korea to over 30% in African countries [10]. Globally, teenage pregnancy is considered to be very high risk due to teenage girls are physically and psychologically immature for reproduction. In addition, some extrinsic factors like inadequate prenatal care, illiteracy, and poor socioeconomic conditions affect the outcome of.
pregnancy in teenage girls [11].
In the developing countries nearly half of all teenage pregnancies are unintended, and more than half of them end in abortion [12]. In addition, studies showed that more than one-third of maternal morbidity and mortality in Africa are attributed to teenage pregnancies [13]. Moreover, teenage pregnancy is associated with adverse perinatal complications, such as preterm births, stillbirths, neonatal deaths, and delivered low birth weight babies [14, 15].
Even though there are studies conducted in SSA countries on the prevalence of teenage pregnancy and adverse birth outcome [16,17,18], studies on that determine the estimated effect of teenage pregnancy on adverse birth outcomes were very limited. This study determines the estimated effect of teenage pregnancy on adverse birth outcomes in SSA by using the most recent DHS data and more advanced model. Moreover, it determines the magnitude of both teenage pregnancy and adverse birth outcome in the region.
Methods
Study design and period
This study was conducted based on Demographic and Health Survey (DHS) data of 8 SSA countries. These Sub-Saharan countries were selected based on the their most recent DHS data availability (from 2020 to 2024) and included Burkina Faso (2021), Cot’ devour (2021), Gahana (2022), Kenya (2022), Lesotho (2024), Mozambique (2023), Senegal (2023) and Tanzania (2022). The DHS is a cross-sectional survey conducted every five years to generate updated health and health-related indicators.
Sample size and sampling techniques
A total weighted sample size of 45,790 with nearly one to ten ratio (teenagers = 4,021 and non-teenagers or elders = 41,769) of reproductive age women who gave birth in the last five years preceding the survey was included. The DHS typically used two stage sampling design. First clusters (Enumeration areas) were selected from sampling frame and secondly within each selected enumeration area households were selected and listed by the field enumerators [19]. The data was obtained from the DHS website; https://dhsprogram.com [20] upon reasonable request via online and then the Birth Record (BR) data of each selected country is appended.
Study variables and their measurements
Outcome variable
The dependent variable of this study was adverse birth outcomes, defined as ‘yes’ when a woman had at least one of the followings: stillbirth, preterm birth, Low Birth Weight (LBW), and macrosomia. Stillbirth was derived from v233 and defined as pregnancy loss occurring after 7 completed months of gestation [21]. Preterm birth was obtained from the DHS question “duration of pregnancy for the most recent birth (b20)” and defined as births after 28 weeks and before 37 weeks of gestational age [22]. Whereas LBW and macrosomia were derived from the DHS question “birth weight in kilograms (m19)” and defined as weight at birth less than 2500 grams; ≥4000 grams respectively [23].
Comparison groups and categories for adverse pregnancy outcome
The treatment variable of our study was age of the women during their recent pregnancy. The treatment group was those women whose recent pregnancy happened 15–19 years of their age (teenagers) and the control group was those women whose recent pregnancy happened at 20–49 years of their age (non-teenagers).
Covariates
Variables that have an effect on teenage pregnancy and adverse birth outcomes at the same time were included. Variables like residence, maternal education, marital status, sex of household head, media exposure, household wealth status, maternal working status, ANC follow-up, Place of delivery and country were considered covariates for matching. Confounding variables that have a significant association with the treatment and outcome variables were considered for matching.
Data management and analysis
All reported results were based on weighted data adjusted for design and non-response using the weighting variable (v005). Primary sampling units (v023) and clustering (v021) were accounted for using the svy declaration to ensure accurate estimation of standard errors and confidence intervals. In cross-sectional studies like DHS random assignment of participants to the treatment and control groups is impossible. Thus, inherent imbalance of the observed variables introduces bias and influences the causal effect of the exposure. In such conditions balancing score can be used to correct bias related to participants assignment to either group. Based on the balancing score, the observed variables should be independent of the assignment of the exposure, teenage pregnancy or not [24, 25].
The propensity score method is commonly used to balance the inequality of confounding variables in such cross-sectional studies [24]. A propensity score is the likelihood that a woman is being in the treatment group (teenagers) given all the observed covariates and it has a value between 0 and 1. Propensity score analysis starts with an assessment of the imbalance of the baseline covariates between the teenagers and non-teenagers. This can be assessed by significance tests like an independent t-test for continuous variables and chi2 for categorical variables [25, 26].
Stata version 17 software was used to perform our analysis. The imbalance of the baseline covariates between the teenagers and non-teenagers was assessed by chi-square test. Accordingly, variables with p-value ≤ 0.05 were considered as candidate covariates for propensity matching analysis [26].
Propensity Score Matching (PSM) analysis
The PSM was performed based on the assumptions of conditional independence assumption (CIA) or un-confoundedness and common support. First, propensity score (PS) was estimated based on the probit model using the above-mentioned matching variables. We had also imposed the common support option to improve the matching quality [27]. The command “pscore” in STATA was used to estimate the PS. We then performed PSM analysis using the command “psmatch2” in STATA to obtain the average treatment effect on the population (ATE), the average treatment effect on the treated (ATT), and the average treatment effect on the untreated (ATU). We tested kernel, nearest neighbor and radius matching algorisms and the nearest neighbor (10) produced better covariate balance and selected as the best matching algorism for our analysis. Besides, nearest neighbor method estimates the average treatment effect for the treated (ATT) and for the untreated (ATU) and enables matching with the smallest possible average propensity score differences between treated and untreated participants [28, 29].
We estimated the average effect of teenage pregnancy on adverse birth outcome by using PSM analysis. In this approach we assumed that AiT is to be adverse birth outcomes teenagers (treatment group), and AiC denotes adverse birth outcomes non-teenagers (control group). The observed outcome (Ai) can be written as Ai=(1 − Ti) AiC + TiAiJ, where Ti = 0, and 1 denotes treatment assignment (age at recent pregnancy). Hence, our interest is to estimate the average treatment effect on the treated (ATT), E (AiT−AiC/Ti = 1). This cannot be estimated directly since normally observed neither AiT for Ti = 0 nor AiC for Ti = 1 is not known.
Quality of matching was tested using the command “pstest” in STATA. The covariates’ distribution between intervention and control group (before & after matching) were assessed using standardized bias, two-sample t-test results, pseudo-R2, and likelihood ratio (LR) test for joint insignificance. Accordingly, matching method that provided the best results; significant reduction in standardized bias in the matched groups as compared to unmatched groups; mean absolute bias value < 5% in the two-sample t-test, P-value > 0.05 and Pseudo R2 and LR test = minimum pseudo-R2 and LR test was selected [24, 30].
We also checked whether the final PSM estimates are sensitive for hidden bias and the robustness of the model by using Mantel–Haenszel (MH) test statistic. The gamma coefficient (Γ) was the factor by which unobserved confounders would affect the assignment into intervention for a treated participant compared to an untreated participant with matching covariates [31]. The range of gamma specified was between 1 and 2 with 0.05 increments. Sensitivity analysis was performed using the STATA command “mhbounds”. The test showed that over, under or acceptable level of estimation of treatment effect [32].
Results
Sociodemographic characteristics and recent pregnancy history of respondents
This study included 45,790 reproductive age women who gave birth in the last five years preceding the survey. The study used 41,769 non-teenagers as control group and 4,021 teenagers as treatment group. Around 28% of teenagers and 35% of non-teenagers reside in urban areas. Similarly, over one-fourth (28.92%) and one-third (38.48%) of teenagers and non-teenagers had no formal education and majority (65.03% and 87.72%) of them were currently married or living with a partner respectably. In the same way, most (62.99% and 70.27%) of teenagers and non-teenagers also had media exposure and around half (46.83% and 55.41%) were from poor wealth status respectively. Majority of the women had ANC follow-up (around 95%) and delivered at health facilities (around 83%) for their recent pregnancy (Table 1).
The magnitude of teenage pregnancy was 8.7% (95% CI: 0.085, 0.090) with the highest and the lowest prevalence observed in Mozambique (15.59%) and Ghana (5.86%) respectively. The magnitude of adverse birth outcome among teenagers, non-teenagers and general population was (45.4%, 39.9% and 40.41%) respectively. In the same way, adverse birth outcome was observed high in Senegal (52.04%) and low in Kenya (27.28%) (Fig. 1).
Our study found that the around one-fourth (25.8% and 25.11%) of teenagers and non-teenagers had faced macrosomia in their recent birth respectively. On the other hand, almost one in hundred (0.99%) teenagers and one in thirty-three (3.26%) non-teenagers had still birth in their recent birth (Fig. 2).
Estimation of propensity score
Before PSM, the baseline variables showed significant differences in adverse birth outcome with p-value of ≤ 0.05. These variables including residence, women education, current marital status, women’s education status, religious, number of five and under years children, current working status of a woman, media exposure, wealth index, women’s current working status, ANC follow-up for most recent pregnancy, place of delivery for most recent birth and country. The strength, direction and significance of the coefficients are shown in the table below (Table 2).
Impact of teenage pregnancy on adverse birth outcome
Nearest neighbor matching with 1 to 10 ratio (10) was used to estimate the Average Treatment Effect (ATE), Average Treatment on Treated (ATT), and Average Treatment on Untreated (ATU). Differences in the mean outcome in matched samples can be utilized to obtain these estimates. The calculated ATT values in the treatment and untreated groups were 0.454 and 0.407, respectively, indicating that adverse birth outcome was increased by 4.7% due to teenage pregnancy by considering other confounders constant. Similarly, the calculated ATU values in the treated and untreated groups were 0.399 and 0.447, respectively. This means adverse birth outcome in the control group (pregnancy after age of 19) had decreased by 4.8%. The average treatment on the study population (ATE) was found to be 4.6% (Table 3).
Quality of matching
Common support
The distributions are almost similar for both teenager and non-teenager groups after matching on PS. The presence of significant overlap between the characteristics of teenager and non-teenager groups proved the validity of the common support assumption. The mean PS was 0.088, with variance of 0.004 and standard deviation of 0.066 between the intervention and control group. The balancing property was satisfied and the region of common support between the two groups was ranging from 0.019 to 0.385 of the PS and all were on-support region (Fig. 3). the final number of blocks was thirteen.
Balancing test
The difference between the unmatched and matched pairs was evaluated by t-statistic and the significance level was determined by its p-value. Our result showed that there was no significant mean difference (p > 0.05) across almost all factors after matching, despite a significant mean difference across all covariates before matching. This indicates that the variables were all sufficiently balanced (Table 4).
Standard bias and model significance
This study aimed to determine the estimated effect of teenage pregnancy on adverse birth outcome. In observational studies the observed association between the exposure and outcome possibly explained by chance (random error), bias (systematic error), effect-cause (reverse causality), confounding and cause-effect. Despite the DHS data is prone to recall and social desirability bias, this potential error is likely to be at random between the treatment and control groups and the observed effect is very unlikely to be due to chance. It is possible that unmeasured predictors of the outcome variables might play a role in the relationship. However, the standardized percent bias and sensitivity analysis indicated that the estimated effects were robust to unmeasured covariates (Fig. 4 ).
The mean and median biases considerably lowered once the intervention and control groups were matched. The mean absolute bias in the unpaired sample decreased from 18.6 to 1.4% after the treated and control groups were matched. The mean bias after matching is less than 5% threshold and shows that the model’s quality matching has improved. The median bias also decreased from 18.6% in the unmatched to 0.7% after matching. The overall significance of the model was assessed using the LR and pseudo R2 tests. After matching, the pseudo-R2 was less than 0.001 and the LR-chi2 test was 5.79 with p-vale of 0.761, suggesting that there was no systematic variation in the covariate distribution between the treated and control groups (Table 5).
Sensitivity analysis
The sensitivity analysis was performed using the Mantel–Haenszel statistic to estimate the extent of unobservable covariates biases on our inferences about the impact of teenage pregnancy on adverse outcome. The QMH test statistic yields the same result when no hidden bias (Γ = 1) is assumed, suggesting a strong treatment effect. Our result showed where Γ = 1, the QMH test statistic is 1.243 for adverse birth outcome. At gamma ≥ 1.3 both over- and under-estimation test statistics show highly significant results (p < 0.001), indicating that the association between teenage pregnancy and adverse birth outcomes is robust to moderate levels of unmeasured confounding (Table 6).
Discussion
The objective of this study was to estimate the effect of teenage pregnancy on adverse birth outcomes. It also determined the magnitude of teenage pregnancy and adverse birth outcome in the study region. Accordingly, the magnitude of teenage pregnancy was 8.7%. This finding was lower than studies done in the sub-Saharan Africa [10, 33]. The variation may be due to the study population difference, as the first systematic review includes all pregnancy history between the age of 13–19 and the second study includes all 15–19 years women who gave birth or being pregnant at the time of data collection while our study included only 15–19 years women who gave births with last five years prior to the survey. In the same way, the magnitude of teenage pregnancy in our study was lower than a systematic review conducted in Africa. This difference may be due to the previous study includes women aged 13–19 while ours only 15–19 years in the study population. Additionally, our study didn’t include countries with higher prevalence like Ethiopia and western Africa in the previous studies [10].
Our study also showed that magnitude of adverse outcomes among teenagers and non-teenagers were 45.4% and 39.9% respectively. From our PSM analysis result 4.7% of the adverse birth outcomes was attributed for teenage pregnancy. The finding was supported by previous studies conducted in central Africa, and Tigray region in Ethiopia [34, 35]. It was also congruent with previous studies which stated as early adolescent pregnancy significantly increased the occurrence of adverse birth outcomes [36,37,38]. The increased risk of adverse birth outcomes may be due to teenagers may not be fully developed to handle the physical demands of pregnancy and dual burden of needing nutrients for their own growth and that of the fetus [39]. Furthermore, teenagers may delay or miss health care seeking due to lack of awareness, stigma, or financial constraints [40]. The study also found that one in five of the study participants had adverse birth outcomes and it was lower than previous study done in sub-Sahara Africa [41]. The variation may be due to that this study included Liberia, Madagascar and Rwanda which had lower prevalence of adverse birth outcome while ours didn’t due to lack of recent DHS data.
This study also showed that the magnitude of low birth weight and pre-term birth were higher among teenagers. The finding was supported by previous studies done in Japan, Tigray region in Ethiopia north west Ethiopia and rural eastern Ethiopia [35, 42,43,44]. On the other hand, in this study still birth was slightly lower among teenagers and macrosomia was happened almost equally among teenagers and non-teenagers. This finding was also inline with previous study done in Ethiopia [43].
Strength and limitation of the study
This study was done based on nationally representative DHS data with a high response rate and standardized questionnaire for the data collection. The study uses large sample size which enhances the reliability, precision and generalizability of the findings. The study also adjusted for the potential confounders using the PSM approach in the estimation of impact of teenage pregnancy on adverse pregnancy outcomes.
However, the matching was done based on the observed variables only, and there may be a possibility of residual confounding (unobserved variables). Moreover, the outcome variable; adverse birth outcomes is self-reported; the magnitude may be decreased due to social desirability.
Policy implication of the study
This study highlighted that the magnitude of teenage pregnancy was significant and its effect on adverse birth outcomes needs a policy attention. The policy makers and implementers can use the findings of this study as evidence showing the burden of teenage pregnancy and specific adverse birth outcomes. As the study showed the effect among each country and specific adverse birth outcomes, the countries can design their specific problem addressing strategies.
Conclusion and recommendation
This study found that around one in ten teenagers had pregnancy between the age of 15 and 19 years and nearly half (45.4%) of them had adverse birth outcome. Furthermore, the result showed that 4.7% of the adverse birth outcomes were attributed by teenage pregnancy.
Thus, the authors recommend for policy makers and programmers to design policies and interventions focused on accessing prenatal care, family planning and comprehensive sexual education specifically for teenagers. Public health campaigns could be launched to raise awareness about the risks of teenage pregnancy and the importance of early and regular prenatal care. In addition, support laws and policies to prevent early marriages and pregnancies. Community-based service provision approach can help to reduce stigma and cultural barriers around contraceptive use and prenatal service use among teenagers.
Data availability
Data is available online and any one can access it from www.measuredhs.com.
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Acknowledgements
We would like to acknowledge the owner of the DHS data, and study participants.
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GT designed the study, performed analysis, interpreted the result and prepared a manuscript. ED, AYA, CTT, NW, TZT, NDB and AH participated in the development of the study proposal, analysis and interpretation of the paper and the manuscript. All authors read, revised, and approved the final manuscript.
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Since we used secondary data and had no direct interaction with the study participants, ethical clearance was not required for this study. The DHS Study administered written informed consent to study participants. We submitted an online request to have permission to access the data. The data was obtained from the DHS program’s measure at http://www.dhsprogram.com. The details of the ethical approval for the Demographic and Health Surveys (DHS) program make it possible to approve the download of survey data.
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Teshale, G., Dellie, E., Aschalew, A.Y. et al. Estimated effect of teenage pregnancy on adverse birth outcome in Sub-Saharan African countries: propensity score matching analysis of recent demographic and health survey data. BMC Pregnancy Childbirth 25, 442 (2025). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12884-025-07574-4
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DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12884-025-07574-4